The 2011 Science Slant Gift List is Here!

We know a lot of you don't seem to have enough hours in the day this time of year, but what does seem to keep getting longer are your holiday shopping lists. If that sounds familiar we're happy to tell you that this is it. This is going to be YOUR year. The year you get it all done well before the holidays even start--with gifts that are educational, or fun, or fun and educational, or just plain strange--so you can wow your friends, impress the smarties and, perhaps more importantly, one-up your rotten sister's 'best aunt' status.

That's because we LabGrabbers have taken it upon ourselves to do all the exhaustive gift searching for you! The result is our annual Science Slant Holiday Gift List, and this year's list might just be our best one yet. From clothing and toys to gadgets and games (what do you mean your best friend doesn't have an EEG mindset yet?) the guide is packed with a slew of science-slanted gifts. We're pretty sure there really is something for everyone so enjoy the guide, pick some gifts and get back to what's really important (hint: holiday buffets!). If you can't find anything in 2011 that fits try our 2009 gift list or 2010 gift list.

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LabGrab 2011 Science Gift Guide

Orcein and O4: Preventing toxic effects of amyloid fibril precursors

A German research team has recently uncovered evidence that orcein, a compound used for hundreds of years as a food dye, and the related compound O4 both act to accelerate the aggregation of β-amyloid monomers into mature amyloid plaques.

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Orcein, O4, Inhibition of amyloid intermediates, Alzheimers, Jeffrey Serrill

ZnO Nanoparticles: Are those sunscreens that you're putting on your skin really safe?

A Swiss/Australian research team has utilized an interesting method for assessing whether or not sunscreens containing certain zinc oxide products could pose any potentially harmful health consequences to consumers.

Zinc Oxide nanomaterials are characterized by several unique optical properties which make them particularly well-suited for use in ultraviolet “optoelectronics” that can act as transducers to convert an optical signal to an electrical one (or vice-versa). These same optical properties, most notably a high level of optical UVA and UVB absorption, have led to the inclusion of these materials in a variety of sunscreen formulations in an attempt to minimize skin damage caused by sunlight. Additionally, these ZnO formulations tend to provide excellent transparency when applied topically, and from a cosmetic industry standpoint, any method of increasing this transparency should be highly advantageous.

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ZnO Nanoparticles in Sunscreen Jeffrey Serrill LabGrab

Clean, green, renewable biofuels from bacteria

US Department of Energy researchers from the Joint BioEnergy Institute (JBEI) reported in a recent paper that they have engineered the first bacterial strain that can digest the biomass of non-food crops and synthesize the sugars into all three forms of transportation fuel - gasoline, diesel and jet biofuels.

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Strains of modified E. coli bacteria - JBEI

A "Brinicle" ... what the heck is that?

A "Brinicle" ... what the heck is that?

Yup - that's exactly what we said when we saw this article from Nature news ... 'Brinicle' ice finger of death....

In the Antarctic, as new sea ice forms on the ocean surface it leaves behind brine that is so salty and dense, it rapidly sinks towards the sea floor. As this salty slurry sinks, it instantly freezes the water surrounding it - forming a salt icicle, or a brinicle - which freezes everything in its spidery path, including starfish and sea urchins.

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Capturing a Brinicle forming - Credit: D. Anderson, BBC

Maybe Einstein was right after all....

In late September we reported the "faster than the speed of light" claim from CERN researchers working on the OPERA project.

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Large Hadron Collider - CERN, Switzerland

Further Details: Parkinson's Protein, alpha-Synuclein, Re-characterized

Earlier this summer, a team of researchers led by Dennis J. Selkoe of Harvard Medical School published a potentially significant finding in Nature suggesting that alpha-synuclein, the protein that aggregates into insoluble fibrils within Lewy bodies in patients with Parkinson’s disease, has been mischaracterized. In contrast previous understanding of alpha-synuclein as a natively unstructured protein, Selkoe and his lab proposed that alpha-synuclein naturally exists as a stable tetramer before destabilization and pathological aggregation. In a push forward in Parkinson’s disease research, a recent independent study by the Petsko-Ringe and Pochapsky laboratories at Brandeis University in Waltham, MA, confirmed the hypothesis by Selkoe and colleagues. The finding is supported by analytical techniques--namely NMR and circular dichroism spectroscopy--different from the Selkoe lab and is published in the October 25 issue of the Proceedings of the National Academy of Sciences.

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Is it now proposed that alpha-synuclein exists as a tetramer.

New Mouse Model Reveals Key Information for Infant Breathing Disorder

Scientists' discovery of new form of neonatal respiratory distress syndrome offers clues to treatments for infants who don't respond to steroid drugs

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These microscopic images of lung tissue from newborn mice

Autistic Children May Have Distinct Facial Characteristics

According to a group of researchers led by Dr. Kristina Aldridge, an assistant professor of anatomy at the University of Missouri School of Medicine and the Thompson Center for Autism and Neurodevelopmental Disorders, certain facial features of children with autism are distinctly different compared to those of typically developing children. Using a 3-D cranial imaging system, the scientists found that autistic compared to non-autistic boys aged 8 to 12 years have a broadened upper face, including wider eyes, shortened middle region of the face, including the cheeks and nose, and broadened mouth and philtrum, the cleft between the nose and upper lip. Additionally, two subgroups of autistic boys had facial morphology different from the majority of other autistic and typically developing boys. These findings published in the October 14, 2011 issue of Molecular Autism suggest that there are potentially multiple etiologies and genetic differences that can lead to autism.

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Boys with autism have distinct facial morphologies compared to typical children

A Not-So-Bright Idea

Numerous studies are beginning to suggest that excessive exposure to white light emitting diodes (LEDs), especially at night, may have adverse effects on our brain’s circadian rhythms. Specifically, these perturbations to our biological clocks can disrupt sleep patterns and reduce the production of hormones such as melatonin, an antioxidant compound that protects DNA from damage, by as much as 25% according to model-based calculations headed by Mark Rea, director of the Lighting Research Center at Rensselaer Polytechnic Institute in Troy, N.Y.

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White LEDs can have adverse affects on our biological clocks