stem cells
Meet Roku, Hex, and Chimero: the World's First Chimeric Monkeys
Researchers at Oregon Health Sciences University (OHSU) have created the world’s first chimeric monkeys, which may contain as many as six distinct genomes. Named Roku, Hex, and Chimero, these rhesus monkeys were produced by successfully aggregating multiple embryos and implanting the mixed embryo into a surrogate mother.
Read more...Muscle-derived stem cell transplantation helps curb age-related degeneration
University of Pittsburgh researchers have recently published a study suggesting that a certain type of stem cell transplantation may help rescue some of the cellular deficiencies which occur as part of the normal aging process.
Read more...Using Stem Cells to Mend a Broken Heart
In a fitting tribute to Valentine's Day, the British Health Foundation (BHF) launched an $80 million dollar research project at the beginning of this 'love' month to investigate using stem cells to regenerate heart tissue and "mend broken hearts".
Read more...Landmark Stem Cell Therapy Clinical Trial Begins
On Monday, October 11th, Geron Corporation of Menlo Park, CA announced the enrollment of the first patient in the company's clinical trial of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells - marking the start of the world's first clinical trial for stem cell based therapies.
Read more...A Future Alternative to Dentures, Regenerate Teeth Using Stem Cells
NEW YORK (May 24, 2010) - A technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, can orchestrate stem cells to migrate to a three-dimensional scaffold infused with growth factor, holding the translational potential to yield an anatomically correct tooth in as soon as nine weeks once implanted.
People who have lost some or all of their adult teeth typically look to dentures, or, more recently, dental implants to improve a toothless appearance that can have a host of unsettling psycho-social ramifications. Despite being the preferred (but generally painful and potentially protracted) treatment for missing teeth nowadays, dental implants can fail and are unable to "remodel" with surrounding jaw bone that undergoes necessary changes throughout a person's life.
Read more...Scientists Discover Key Step for Regulating Embryonic Development
HOUSTON – Deleting a gene in mouse embryos caused cardiac defects and early death, leading researchers to identify a mechanism that turns developmental genes off and on as an embryo matures, a team led by a scientist at The University of Texas M. D. Anderson Cancer Center reported today in Molecular Cell.
Read more...MGE Cells Offer Hope for Repairing Damaged Neural Circuits
Scientists working to understand more about the brains ability to learn and change in relation to the age of the cells have reported a new finding that they were able to prompt a new period of plasticity in the brain of juvenile mice. Their study involved the transplant a specific type of immature neuron from embryonic mice to the visual cortex of juvenile mice. The visual cortex has a period of very high plasticity during the earliest stages of development. During the period of plasticity, cells in this region react strongly to visual cues and respond with rapid synaptic transmissions produce the neural circuitry that is crucial for proper visual function.
Read more...New DNA technique leads to a breakthrough in child cancer research
Researchers at the Sahlgrenska Academy and Karolinska Institutet have used novel technology to reveal the different genetic patterns of neuroblastoma, an aggressive form of childhood cancer. This discovery may lead to significant advances in the treatment of this malignant disease, which mainly affects small children.
Read more...An Enzyme That Can Effectively Wipe a Cell’s Developmental Slate Clean
Howard Hughes Medical Institute (HHMI) researchers and their colleagues have identified an enzyme that can effectively wipe a cell’s developmental slate clean, essentially giving a fresh start. The enzyme, which is thought to help genetically reprogram fertilized eggs as part of normal development, may help scientists create stem cells and arrest the growth of cancers.
Read more...Cancer Stem Cell Regulatory Gene Identified
Cancer stem cells have many of the same characteristics as regular stem cells - and are thought to be directly responsible for tumor formation and growth. Tufts University researchers have recently identified that the STAT3 gene regulates cancer stem cells in the aggressive brain cancer, Glioblastoma multiforme (GBM) - offering a promising new option in the fight against such cancers.
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