synthetic biology

Synthetic nucleoside allows in vivo visualization of DNA synthesis

A novel strategy has recently been developed which allows the visualization of DNA synthesis in intact cells or organisms. This strategy, developed by the University of Zurich’s Institute of Organic Chemistry, utilizes a tailor-made nucleic acid which can be incorporated into a normal DNA strand to allow this biochemical process to be seen using fluorescent probes.

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 Jeffrey Serrill, synthetic nucleosides, in vivo DNA synthesis, F-ara-Edu

EU Survey Says!

Europe's latest public opinion poll shows concern yet optimism toward emerging technologies and new fields within science. A clear optimistic trend appears in this latest report, "Europeans and biotechnology in 2010 Winds of change?". This is of course balanced with a public concern for safety and a need for further public awareness on some topics.

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Europeans and biotechnology in 2010 Winds of change?
Europeans and biotechnology in 2010 Winds of change?

"TO LIVE, TO ERR, TO FALL, TO TRIUMPH, TO RECREATE LIFE OUT OF LIFE"

In a post we made in early March of this year, we reported on an interview with Dr. J. Craig Venter. In the video Dr. Venter mentioned their team was close to producing cells from an entirely synthetic DNA genome.

Today the research team announced 'success' ... they have designed a genome in the computer, chemically made it in the lab, transplanted it into a recipient cell and now have produced a new self-replicating cell, controlled only by the synthetic genome.

It has taken the team the better part of 15 years to arrive at this important stage. Dr. Daniel Gibson, lead author on the published article, stated, “To produce a synthetic cell, our group had to learn how to sequence, synthesize, and transplant genomes. Many hurdles had to be overcome, but we are now able to combine all of these steps to produce synthetic cells in the laboratory.” He added, “We can now begin working on our ultimate objective of synthesizing a minimal cell containing only the genes necessary to sustain life in its simplest form. This will help us better understand how cells work.”

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JCVI Synthetic Biology Team Members

Mimicking the Gecko

Researchers at the University of California, Berkeley continue to edge closer to producing a synthetic adhesive that will be able to replicate the tiny hairs found on the toes of the gravity defying gecko lizard.

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